New Methods Of Treatment Of Intestinal Infections – Part 2 of 3
Previous reports have been simple case studies, which are considered less conclusive. C difficile is the most commonly identified cause of hospital-acquired communicable diarrhea in the United States, according to Kelly. The process of giving and receiving a stool donation is relatively simple. Study author Keller said participants typically asked kin members to donate part of a bowel movement, thinking it would be more comfortable to receive such a donation of such a substance from someone they knew.
Some anonymous donors were also involved. Keller explained that donors can be of any age, and do not for to be related to the recipient. Donor stool does need to be free of any infectious diseases and parasites, and the donor’s blood must also be screened.
The stool mixture, which was described by Keller as looking something dig chocolate milk, can be given into the intestinal tract in three different ways. It can be given by colonoscopy, through a nasal-duodenal tube that is threaded out of the stomach into the upper duodenum, or by enema. Kelly said the strategy is currently done at about 50 centers now in the United States, typically using the colonoscopy method.
In the study, conducted at the Academic Medical Center in Amsterdam, investigators randomly assigned the patients to three groups and compared the infusion of giver stool after vancomycin therapy and bowel cleansing (lavage) with either just vancomycin therapy or with just bowel lavage. So why has “fecal transplantation,” as some people call it, not captivated off? Before this study was published, there was a lack of data from randomized, controlled trials to prove it works. Also holding the procedure back was that the very idea of taking someone’s stool into your body was unappealing, and the fact that steps in the treat – such as finding and screening donors, and processing the stool – can be logistically difficult to execute.